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A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition

Viral encephalitis is a significant cause of human morbidity and mortality in large part due to suboptimal diagnosis and treatment. Murine reovirus infection serves as a classic experimental model of viral encephalitis. Infection of neonatal mice with T3 reoviruses results in lethal encephalitis ass...

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Detalhes bibliográficos
Main Authors: Dionne, Kalen R., Leser, J. Smith, Lorenzen, Kristi A., Beckham, J. David, Tyler, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060973/
https://ncbi.nlm.nih.gov/pubmed/21241693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2011.01.006
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