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Effect of proline position on the antimicrobial mechanism of buforin II

Buforin II (BF2) is a histone-derived antimicrobial peptide that causes cell death by translocating across membranes and interacting with nucleic acids. It contains one proline residue critical for its function. Previous research found that mutations replacing proline lead to decreased membrane tran...

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Bibliografiske detaljer
Main Authors: Xie, Yang, Fleming, Eleanor, Chen, Jessica L., Elmore, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060972/
https://ncbi.nlm.nih.gov/pubmed/21277926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.01.010
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