Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease

BACKGROUND: The non-pathogenic course of SIV infection in its natural host is characterized by robust viral replication in the absence of chronic immune activation and T cell proliferation. In contrast, acutely lethal enteropathic SIVsmm strain PBj induces a strong immune activation and causes a sev...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tschulena, Ulrich, Sanzenbacher, Ralf, Mühlebach, Michael D, Berger, André, Münch, Jan, Schindler, Michael, Kirchhoff, Frank, Plesker, Roland, Coulibaly, Cheick, Panitz, Sylvia, Prüfer, Steffen, Muckenfuss, Heide, Hamdorf, Matthias, Schweizer, Matthias, Cichutek, Klaus, Flory, Egbert
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060844/
https://ncbi.nlm.nih.gov/pubmed/21366921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-14
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky