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S1 nuclease sensitivity of a double-stranded telomeric DNA sequence.

We examined structural properties of poly d(C4A2).d(T2G4), the telomeric DNA sequence of the ciliated protozoan Tetrahymena. Under conditions of high negative supercoiling, poly d(C4A2).d(T2G4) inserted in a circular plasmid vector was preferentially sensitive to digestion with S1 nuclease. Only the...

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Autors principals: Budarf, M, Blackburn, E
Format: Artigo
Idioma:Inglês
Publicat: 1987
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC306083/
https://ncbi.nlm.nih.gov/pubmed/2819822
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