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Sublancin is not a lantibiotic but an S-linked glycopeptide

Sublancin is shown to be an S-linked glycopeptide containing a glucose attached to a Cys residue, establishing a new post-translational modification. The activity of the S-glycosyl transferase was reconstituted in vitro and the enzyme is shown to have relaxed substrate specificity allowing the prepa...

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Main Authors: Oman, Trent J., Boettcher, John M., Wang, Huan, Okalibe, Xenia N., van der Donk, Wilfred A.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060661/
https://ncbi.nlm.nih.gov/pubmed/21196935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.509
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