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Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis
It has been 100 years since the first report of sickle haemoglobin (HbS). More than 50 years ago, it was suggested that the gene responsible for this disorder could reach high frequencies because of resistance conferred against malaria by the heterozygous carrier state. This traditional example of b...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060623/ https://ncbi.nlm.nih.gov/pubmed/21045822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1104 |
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