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Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
Influenza virus sialidase has an essential role in the virus' life cycle. Two distinct groups of influenza A virus sialidases have been established, that differ in the flexibility of the '150-loop', providing a more open active site in the apo form of the group-1 compared to group-2 e...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060605/ https://ncbi.nlm.nih.gov/pubmed/21081911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1114 |
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