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A model for the separation of large DNA molecules by crossed field gel electrophoresis.

The idea that large DNA molecules adopt a stretched conformation as they pass through gels suggests a simple mechanism for the separation of DNA by crossed field electrophoresis: at each change in field direction a DNA molecule takes off in the new direction of the field by a movement which is led b...

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Detalhes bibliográficos
Main Authors: Southern, E M, Anand, R, Brown, W R, Fletcher, D S
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306059/
https://ncbi.nlm.nih.gov/pubmed/3627974
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