Accurate, large-scale genotyping of 5HTTLPR and flanking SNPs in an association study of depression, anxiety and personality measures

BACKGROUND: 5HTTLPR, the length polymorphism repeat in the promoter region of the serotonin transporter gene (5HTT renamed SLC6A4) is one of the most studied polymorphisms for association with a range of psychiatric and personality phenotypes. However, the original 5HTTLPR assay is prone to bias tow...

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Autori principali: Wray, Naomi R, James, Michael R, Gordon, Scott D, Dumenil, Troy, Ryan, Leanne, Coventry, William L, Statham, Dixie J, Pergadia, Michele L, Madden, Pamela AF, Heath, Andrew C, Montgomery, Grant W, Martin, Nicholas G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060567/
https://ncbi.nlm.nih.gov/pubmed/19541292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.04.030
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