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Extracellular Hepatitis C Virus Core Protein Activates STAT3 in Human Monocytes/Macrophages/Dendritic Cells via an IL-6 Autocrine Pathway

Hepatitis C virus (HCV) infection is highly efficient in the establishment of persistent infection, which leads to the development of chronic liver disease and hepatocellular carcinoma. Impaired T cell responses with reduced IFN-γ production have been reported to be associated with persistent HCV in...

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Bibliografiske detaljer
Main Authors: Tacke, Robert S., Tosello-Trampont, Annie, Nguyen, Virginia, Mullins, David W., Hahn, Young S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060535/
https://ncbi.nlm.nih.gov/pubmed/21282107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.217653
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