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Exercise Increases Mitochondrial PGC-1α Content and Promotes Nuclear-Mitochondrial Cross-talk to Coordinate Mitochondrial Biogenesis

Endurance exercise is known to induce metabolic adaptations in skeletal muscle via activation of the transcriptional co-activator peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α). PGC-1α regulates mitochondrial biogenesis via regulating transcription of nuclear-encoded mitochond...

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Detalhes bibliográficos
Main Authors: Safdar, Adeel, Little, Jonathan P., Stokl, Andrew J., Hettinga, Bart P., Akhtar, Mahmood, Tarnopolsky, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060512/
https://ncbi.nlm.nih.gov/pubmed/21245132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211466
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