Ectodomain Shedding and Autocleavage of the Cardiac Membrane Protease Corin

Corin is a cardiac membrane protease that activates natriuretic peptides. It is unknown how corin function is regulated. Recently, soluble corin was detected in human plasma, suggesting that corin may be shed from cardiomyocytes. Here we examined soluble corin production and activity and determined...

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Bibliographic Details
Main Authors: Jiang, Jingjing, Wu, Shannon, Wang, Wei, Chen, Shenghan, Peng, Jianhao, Zhang, Xiumei, Wu, Qingyu
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060458/
https://ncbi.nlm.nih.gov/pubmed/21288900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185082
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