TRPC6 Enhances Angiotensin II-induced Albuminuria

Mutations in the canonical transient receptor potential cation channel 6 (TRPC6) are responsible for familial forms of adult onset focal segmental glomerulosclerosis (FSGS). The mechanisms by which TRPC6 mutations cause kidney disease are not well understood. We used TRPC6-deficient mice to examine...

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主要な著者: Eckel, Jason, Lavin, Peter J., Finch, Elizabeth A., Mukerji, Nirvan, Burch, Jarrett, Gbadegesin, Rasheed, Wu, Guanghong, Bowling, Brandy, Byrd, Alison, Hall, Gentzon, Sparks, Matthew, Zhang, Zhu Shan, Homstad, Alison, Barisoni, Laura, Birbaumer, Lutz, Rosenberg, Paul, Winn, Michelle P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2011
主題:
Basic Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060446/
https://ncbi.nlm.nih.gov/pubmed/21258036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010050522
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