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SGCE isoform characterization and expression in human brain: implications for myoclonus–dystonia pathogenesis?

Myoclonus–dystonia (M–D) is a neurological movement disorder with involuntary jerky and dystonic movements as major symptoms. About 50% of M–D patients have a mutation in ɛ-sarcoglycan (SGCE), a maternally imprinted gene that is widely expressed. As little is known about SGCE function, one can only...

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Detalhes bibliográficos
Main Authors: Ritz, Katja, van Schaik, Barbera DC, Jakobs, Marja E, van Kampen, Antoine H, Aronica, Eleonora, Tijssen, Marina A, Baas, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060322/
https://ncbi.nlm.nih.gov/pubmed/21157498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.206
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