A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease in which the type I interferon pathway has a crucial role. We have previously shown that three genes in this pathway, IRF5, TYK2 and STAT4, are strongly associated with risk for SLE. Here, we investigated 78 genes involved in the ty...

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Main Authors: Sandling, Johanna K, Garnier, Sophie, Sigurdsson, Snaevar, Wang, Chuan, Nordmark, Gunnel, Gunnarsson, Iva, Svenungsson, Elisabet, Padyukov, Leonid, Sturfelt, Gunnar, Jönsen, Andreas, Bengtsson, Anders A, Truedsson, Lennart, Eriksson, Catharina, Rantapää-Dahlqvist, Solbritt, Mälarstig, Anders, Strawbridge, Rona J, Hamsten, Anders, Criswell, Lindsey A, Graham, Robert R, Behrens, Timothy W, Eloranta, Maija-Leena, Alm, Gunnar, Rönnblom, Lars, Syvänen, Ann-Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060320/
https://ncbi.nlm.nih.gov/pubmed/21179067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.197
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