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An Image Based, High-Throughput, Screening Assay For Molecules That Induce Excess DNA Replication In Human Cancer Cells

Previous studies have shown DNA re-replication can be induced in cells derived from human cancers under conditions in which cells derived from normal tissues are not. Since DNA re-replication induces cell death, this strategy could be applied to the discovery of potential anticancer therapeutics. Th...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhu, Wenge, Lee, Chrissie Y., Johnson, Ronald L., Wichterman, Jennifer, Huang, Ruili, DePamphilis, Melvin L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060295/
https://ncbi.nlm.nih.gov/pubmed/21257818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0570
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