ERCC1 and ERCC2 Polymorphisms Predict Clinical Outcomes of Oxaliplatin-based Chemotherapies in Gastric and Colorectal Cancer: A Systemic Review and Meta-analysis

PURPOSE: Nucleotide excision repair (NER) modulates platinum-based chemotherapeutic efficacy by removing drug-produced DNA damage. To summarize published data on the association between polymorphisms of NER genes (ERCC1 and ERCC2) and responses to oxaliplatin-based chemotherapies, we performed a met...

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Hoofdauteurs: Yin, Ming, Yan, Jingrong, Martinez-Balibrea, Eva, Graziano, Francesco, Lenz, Heinz-Josef, Kim, Hyo-Jin, Robert, Jacques, Im, Seock-Ah, Wang, Wei-Shu, Etienne-Grimaldi, Marie-Christine, Wei, Qingyi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060288/
https://ncbi.nlm.nih.gov/pubmed/21278243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2169
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