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Predicting clonal self-renewal and extinction of hematopoietic stem cells

A single hematopoietic stem cell (HSC) can generate a clone, consisting of daughter HSCs and differentiated progeny, which can sustain the hematopoietic system of multiple hosts for a long time. At the same time, this massive expansion potential must be restrained to prevent abnormal, leukemic proli...

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Detalhes bibliográficos
Main Authors: Sieburg, Hans B., Rezner, Betsy D., Muller-Sieburg, Christa E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060234/
https://ncbi.nlm.nih.gov/pubmed/21368169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011414108
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