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The human beta-globin gene contains a downstream developmental specific enhancer.

The human beta-globin gene is part of a multigene family and is expressed specifically in adult human erythroid tissue (for review, 1). When the human beta-globin is introduced into fertilized mouse eggs, it is first activated in foetal liver and remains expressed in adult erythroid tissues. It ther...

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Bibliographic Details
Main Authors: Kollias, G, Hurst, J, deBoer, E, Grosveld, F
Format: Artigo
Language:Inglês
Published: 1987
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC306019/
https://ncbi.nlm.nih.gov/pubmed/3039464
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