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Virulence of H5N1 virus in mice attenuates after in vitro serial passages
The virulence of A/Vietnam/1194/2004 (VN1194) in mice attenuated after serial passages in MDCK cells and chicken embryos, because the enriched large-plaque variants of the virus had significantly reduced virulence. In contrast, the small-plaque variants of the virus and the variants isolated from th...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060145/ https://ncbi.nlm.nih.gov/pubmed/21371335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-93 |
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