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The H93G Myoglobin Cavity Mutant as a Versatile Scaffold for Modeling Heme Iron Coordination Structures in Protein Active Sites and Their Characterization with Magnetic Circular Dichroism Spectroscopy

Preparation of heme model complexes is a challenging subject of long-standing interest for inorganic chemists. His93Gly sperm whale myoglobin (H93G Mb) has the proximal His replaced with the much smaller non-coordinating Gly. This leaves a cavity on the proximal side of the heme into which a wide va...

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Detalhes bibliográficos
Main Authors: Du, Jing, Sono, Masanori, Dawson, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060032/
https://ncbi.nlm.nih.gov/pubmed/21423881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.01.029
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