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A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing

We identify a new mammalian cohesin subunit, RAD21-like protein (RAD21L), with sequence similarity to RAD21 and REC8. RAD21L localizes along axial elements in early meiotic prophase, in a manner that is spatiotemporally different to either REC8 or RAD21. Remarkably, RAD21L and REC8 have symmetrical,...

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Detalhes bibliográficos
Main Authors: Ishiguro, Kei-ichiro, Kim, Jihye, Fujiyama-Nakamura, Sally, Kato, Shigeaki, Watanabe, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059921/
https://ncbi.nlm.nih.gov/pubmed/21274006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.2
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