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Mitochondria supply membranes for autophagosome biogenesis during starvation

Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to lysosomes for degradation, thereby re-supplying depleted nutrients. Despite advances in understanding the molecular basis of this process, the membrane origin of autophagosomes remains unclear. Here, we demonstrat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hailey, Dale W., Kim, Peter K., Satpute-Krishnan, Prasanna, Rambold, Angelika S., Mitra, Kasturi, Sougrat, Rachid, Lippincott-Schwartz, Jennifer
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059894/
https://ncbi.nlm.nih.gov/pubmed/20478256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.04.009
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