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Increased stability of Bcl-2 in HSP70-mediated protection against apoptosis induced by oxidative stress

We have previously shown that heat shock protein 70 (HSP70) markedly inhibits H(2)O(2)-induced apoptosis in mouse C2C12 myogenic cells by reducing the release of Smac. However, the molecular mechanism by which HSP70 interferes with Smac release during oxidative stress-induced apoptosis is not unders...

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Autores principales: Jiang, Bimei, Liang, Pengfei, Deng, Gonghua, Tu, Zizhi, Liu, Meidong, Xiao, Xianzhong
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059790/
https://ncbi.nlm.nih.gov/pubmed/20890773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0226-6
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