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Acetaminophen Pharmacokinetics in Children with Nonalcoholic Fatty Liver Disease

OBJECTIVES: To evaluate UDP-glucuronyltransferase (UGT) activity and the pharmacokinetics of a single oral dose of acetaminophen (APAP) in children with non-alcoholic fatty liver disease (NAFLD). METHODS: Twelve boys 10–17 years old with biopsy-proven NAFLD and 12 age and gender-matched controls wit...

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Detalhes bibliográficos
Main Authors: Barshop, Nicole J., Capparelli, Edmund V., Sirlin, Claude B., Schwimmer, Jeffrey B., Lavine, Joel E
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059772/
https://ncbi.nlm.nih.gov/pubmed/21240014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e3181f9b3a0
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