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Effect of α4β7 Blockade on Intestinal Lymphocyte Subsets and Lymphoid Tissue Development

BACKGROUND: Blockade of the integrin α4β7 has promise as a therapy for inflammatory bowel disease. α4β7 plays diverse roles in the intestinal immune system, including lymphocyte homing and lymphoid tissue formation; however, the effects of α4β7 blockade on these processes during inflammation and the...

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Bibliografische gegevens
Hoofdauteurs: Wang, Caihong, Hanly, Elyse K., Wheeler, Leroy W., Kaur, Manreet, McDonald, Keely G., Newberry, Rodney D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059721/
https://ncbi.nlm.nih.gov/pubmed/20848481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21266
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