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Determination of Methylated CpG Sites in the Promoter Region of Catechol-O-Methyltransferase (COMT) and their Involvement in the Etiology of Tobacco Smoking

We previously reported that catechol-O-methyltransferase (COMT) is significantly associated with nicotine dependence (ND) in humans. In this study, we examined whether there exists any difference in the extent of methylation of CpG dinucleotides in the promoter region of COMT in smokers and non-smok...

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Detalhes bibliográficos
Main Authors: Xu, Qing, Ma, Jennie Z., Payne, Thomas J., Li, Ming D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059640/
https://ncbi.nlm.nih.gov/pubmed/21423427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2010.00016
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