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Determination of Methylated CpG Sites in the Promoter Region of Catechol-O-Methyltransferase (COMT) and their Involvement in the Etiology of Tobacco Smoking

We previously reported that catechol-O-methyltransferase (COMT) is significantly associated with nicotine dependence (ND) in humans. In this study, we examined whether there exists any difference in the extent of methylation of CpG dinucleotides in the promoter region of COMT in smokers and non-smok...

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Autori principali: Xu, Qing, Ma, Jennie Z., Payne, Thomas J., Li, Ming D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059640/
https://ncbi.nlm.nih.gov/pubmed/21423427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2010.00016
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