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GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure

The gene has been proposed as an attractive unit of analysis for association studies, but a simple yet valid, powerful, and sufficiently fast method of evaluating the statistical significance of all genes in large, genome-wide datasets has been lacking. Here we propose the use of an extended Simes t...

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Detalhes bibliográficos
Main Authors: Li, Miao-Xin, Gui, Hong-Sheng, Kwan, Johnny S.H., Sham, Pak C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059433/
https://ncbi.nlm.nih.gov/pubmed/21397060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.01.019
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