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GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure
The gene has been proposed as an attractive unit of analysis for association studies, but a simple yet valid, powerful, and sufficiently fast method of evaluating the statistical significance of all genes in large, genome-wide datasets has been lacking. Here we propose the use of an extended Simes t...
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Autori principali: | , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Elsevier
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059433/ https://ncbi.nlm.nih.gov/pubmed/21397060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.01.019 |
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