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A high throughput assay of diffusion through Cx43 gap junction channels with a microfluidic chip

This paper describes a microfluidic-based assay capable of measuring gap-junction mediated dye diffusion in cultured cells. The technique exploits multi-stream laminar flow to selectively expose cells to different environments, enabling continuous loading of cells in one compartment while monitoring...

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Detalhes bibliográficos
Main Authors: Bathany, Cédric, Beahm, Derek, Felske, James D., Sachs, Frederick, Hua, Susan Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059360/
https://ncbi.nlm.nih.gov/pubmed/21182279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac102658h
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