Sensitivity to cisplatin in primary cell lines derived from human glioma correlates with levels of EGR-1 expression

BACKGROUND: Less than 30% of malignant gliomas respond to adjuvant chemotherapy. Here, we have asked whether variations in the constitutive expression of early-growth response factor 1 (EGR-1) predicted acute cytotoxicity and clonogenic cell death in vitro, induced by six different chemotherapics. M...

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Detalhes bibliográficos
Main Authors: Calogero, Antonella, Porcellini, Antonio, Lombari, Vincenza, Fabbiano, Cinzia, Arcella, Antonietta, Miscusi, Massimo, Ponti, Donatella, Ragona, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059282/
https://ncbi.nlm.nih.gov/pubmed/21366897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-5
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