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A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris

BACKGROUND: Pichia pastoris is one of the most important host organisms for the recombinant production of proteins in industrial biotechnology. To date, strain specific parameters, which are needed to set up feeding profiles for fed batch cultivations, are determined by time-consuming continuous cul...

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Detalhes bibliográficos
Main Authors: Dietzsch, Christian, Spadiut, Oliver, Herwig, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059269/
https://ncbi.nlm.nih.gov/pubmed/21371310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-10-14
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