Relation of serotonin transporter genetic variation to efficacy of escitalopram for Generalized Anxiety Disorder in older adults

OBJECTIVE: Generalized Anxiety Disorder (GAD) is common in older adults and can be treated with SSRIs. Genetic variation in the serotonin transporter gene promoter region is posited to be associated with SSRI efficacy: two polymorphisms (5HTTLPR s/l and rs25531 g/a) form a haplotype with the La comb...

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Autori principali: Lenze, Eric J., Goate, Alison M., Nowotny, Petra, Dixon, David, Shi, Peichang, Bies, Robert R., Lotrich, Francis K., Rollman, Bruce L., Shear, M. Katherine, Thompson, Paul A., Andreescu, Carmen, Pollock, Bruce G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059101/
https://ncbi.nlm.nih.gov/pubmed/21105279
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