Identification of Two Major Conformational Aquaporin-4 Epitopes for Neuromyelitis Optica Autoantibody Binding

Neuromyelitis optica (NMO) is an autoimmune demyelinating disease characterized by the presence of anti-aquaporin-4 (AQP4) antibodies in the patient sera. We recently reported that these autoantibodies are able to bind AQP4 when organized in the supramolecular structure called the orthogonal array o...

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Detalhes bibliográficos
Principais autores: Pisani, Francesco, Mastrototaro, Mauro, Rossi, Andrea, Nicchia, Grazia Paola, Tortorella, Carla, Ruggieri, Maddalena, Trojano, Maria, Frigeri, Antonio, Svelto, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059066/
https://ncbi.nlm.nih.gov/pubmed/21212277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123000
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