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A Novel Inhibitory Domain of Helicobacter pylori Protein CagA Reduces CagA Effects on Host Cell Biology

The Helicobacter pylori protein CagA (cytotoxin-associated gene A) is associated with an increased risk for gastric cancer formation. After attachment to epithelial cells, the bacteria inject CagA via a type IV secretion apparatus into host cells, where it exerts its biological activity. Host cell r...

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Detalhes bibliográficos
Main Authors: Pelz, Christiane, Steininger, Sylvia, Weiss, Claudia, Coscia, Fabian, Vogelmann, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059056/
https://ncbi.nlm.nih.gov/pubmed/21212271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166504
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