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Influenza A virus NS2 protein mediates vRNP nuclear export through NES-independent interaction with hCRM1

For nuclear export of proteins, the formation of a ternary export complex composed of the export substrate, a cellular export factor and Ran-GTP is crucial. CRM1 is a cellular export factor for proteins containing leucine-rich nuclear export signals (NESs). Although the NES sequence is crucial for n...

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Udgivet i:EMBO J
Principais autores: Neumann, Gabriele, Hughes, Mark T., Kawaoka, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305902/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11118210/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.24.6751
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