Parathyroid Hormone-responsive Smad3-related Factor, Tmem119, Promotes Osteoblast Differentiation and Interacts with the Bone Morphogenetic Protein-Runx2 Pathway

The mechanisms whereby the parathyroid hormone (PTH) exerts its anabolic action on bone are incompletely understood. We previously showed that inhibition of ERK1/2 enhanced Smad3-induced bone anabolic action in osteoblasts. These findings suggested the hypothesis that changes in gene expression asso...

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Autors principals: Hisa, Itoko, Inoue, Yoshifumi, Hendy, Geoffrey N., Canaff, Lucie, Kitazawa, Riko, Kitazawa, Sohei, Komori, Toshihisa, Sugimoto, Toshitsugu, Seino, Susumu, Kaji, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058974/
https://ncbi.nlm.nih.gov/pubmed/21239498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179127
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