Bioluminescence Resonance Energy Transfer Reveals the Adrenocorticotropin (ACTH)-Induced Conformational Change of the Activated ACTH Receptor Complex in Living Cells

The melanocortin 2 receptor (MC2R) accessory protein (MRAP) is a small single-transmembrane domain protein that plays a pivotal role in the function of the MC2R. The pituitary hormone, ACTH, acts via this receptor complex to stimulate adrenal steroidogenesis. Using both coimmunoprecipitation and bio...

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Hlavní autoři: Cooray, Sadani N., Chung, Teng-Teng, Mazhar, Khansa, Szidonya, Laszlo, Clark, Adrian J. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Glucocorticoids-CRH-ACTH-Adrenal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058915/
https://ncbi.nlm.nih.gov/pubmed/21177829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1053
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