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GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming

The GreA and GreB proteins of Escherichia coli show a multitude of effects on transcription elongation in vitro, yet their physiological functions are poorly understood. Here, we investigated whether and how these factors influence lateral oscillations of RNA polymerase (RNAP) in vivo, observed at a...

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Bibliographic Details
Main Authors: Toulmé, Francine, Mosrin-Huaman, Christine, Sparkowski, Jason, Das, Asis, Leng, Marc, Rachid Rahmouni, A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305891/
https://ncbi.nlm.nih.gov/pubmed/11118220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.24.6853
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