fMRI brain activation in bipolar mania: Evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway

BACKGROUND: Bipolar I disorder is defined by the occurrence of mania. The presence of mania, coupled with a course of illness characterized by waxing and waning of affective symptoms, suggests that bipolar disorder arises from dysfunction of neural systems that maintain emotional arousal and homeost...

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Main Authors: Strakowski, Stephen M., Eliassen, James C., Lamy, Martine, Cerullo, Michael A., Allendorfer, Jane B., Madore, Michelle, Lee, Jing-Huei, Welge, Jeffrey A., DelBello, Melissa P., Fleck, David E., Adler, Caleb M.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058900/
https://ncbi.nlm.nih.gov/pubmed/21051038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.09.019
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