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Escherichia coli RNA polymerase core and holoenzyme structures

Multisubunit RNA polymerase is an essential enzyme for regulated gene expression. Here we report two Escherichia coli RNA polymerase structures: an 11.0 Å structure of the core RNA polymerase and a 9.5 Å structure of the σ(70) holoenzyme. Both structures were obtained by cryo-electron microscopy and...

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Autors principals: Finn, Robert D., Orlova, Elena V., Gowen, Brent, Buck, Martin, van Heel, Marin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC305883/
https://ncbi.nlm.nih.gov/pubmed/11118218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.24.6833
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