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The formin DAD domain plays dual roles in autoinhibition and actin nucleation
Formins are a large family of actin assembly-promoting proteins with many important biological roles [1-3]. However, it has remained unclear how formins nucleate actin polymerization. All other nucleators are known to recruit actin monomers as a central part of their mechanisms [3-5]. However, the a...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058777/ https://ncbi.nlm.nih.gov/pubmed/21333540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.01.047 |
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