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Immobilization of the early secretory pathway by a virus glycoprotein that binds to microtubules

Membrane trafficking from the endoplasmic reticulum (ER) to the Golgi complex is mediated by pleiomorphic carrier vesicles that are driven along microtubule tracks by the action of motor proteins. Here we describe how NSP4, a rotavirus membrane glycoprotein, binds to microtubules and blocks ER-to-Go...

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Bibliographic Details
Main Authors: Xu, Aimin, Bellamy, A.Richard, Taylor, John A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305877/
https://ncbi.nlm.nih.gov/pubmed/11101519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6465
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