Using the Transcription Factor Inhibitor of DNA Binding 1 to Selectively Target Endothelial Progenitor Cells Offers Novel Strategies to Inhibit Tumor Angiogenesis and Growth

Tumor angiogenesis is essential for malignant growth and metastasis. Bone marrow (BM)-derived endothelial progenitor cells (EPCs) contribute to angiogenesis-mediated tumor growth. EPC ablation can reduce tumor growth, however, the lack of a marker that can track EPCs from the BM to tumor neovasculat...

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Hauptverfasser: Mellick, Albert S., Plummer, Prue N., Nolan, Daniel J., Gao, Dingcheng, Bambino, Kathryn, Hahn, Mary, Catena, Raul, Turner, Vivian, McDonnell, Kevin, Benezra, Robert, Brink, Robert, Swarbrick, Alexander, Mittal, Vivek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058751/
https://ncbi.nlm.nih.gov/pubmed/20807818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1142
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