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MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
Interference with virus entry is known to be the principle mechanism of HIV neutralization by antibodies, including 2F5 and 4E10, which bind to the membrane-proximal external region (MPER) of the gp41 envelope protein. However, to date, the precise molecular events underlying neutralization by MPER-...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058584/ https://ncbi.nlm.nih.gov/pubmed/21357743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101907 |
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