MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1

Interference with virus entry is known to be the principle mechanism of HIV neutralization by antibodies, including 2F5 and 4E10, which bind to the membrane-proximal external region (MPER) of the gp41 envelope protein. However, to date, the precise molecular events underlying neutralization by MPER-...

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Detalhes bibliográficos
Main Authors: Ruprecht, Claudia R., Krarup, Anders, Reynell, Lucy, Mann, Axel M., Brandenberg, Oliver F., Berlinger, Livia, Abela, Irene A., Regoes, Roland R., Günthard, Huldrych F., Rusert, Peter, Trkola, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058584/
https://ncbi.nlm.nih.gov/pubmed/21357743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101907
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