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Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer
Pancreatic cancer is a very aggressive disease characterized by a marked desmoplasia with a predominant Th2 (GATA-3(+)) over Th1 (T-bet(+)) lymphoid infiltrate. We found that the ratio of GATA-3(+)/T-bet(+) tumor-infiltrating lymphoid cells is an independent predictive marker of patient survival. Pa...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058573/ https://ncbi.nlm.nih.gov/pubmed/21339327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101876 |
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