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The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

Members of the mitogen-activated protein kinase (MAPK) cascade such as extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and p38 are implicated as important regulators of cardiomyocyte hypertrophic growth in culture. However, the role that individual MAPK pathways play in vi...

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Detalhes bibliográficos
Main Authors: Bueno, Orlando F., De Windt, Leon J., Tymitz, Kevin M., Witt, Sandra A., Kimball, Thomas R., Klevitsky, Raisa, Hewett, Timothy E., Jones, Steven P., Lefer, David J., Peng, Chang-Fu, Kitsis, Richard N., Molkentin, Jeffery D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC305855/
https://ncbi.nlm.nih.gov/pubmed/11101507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6341
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