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Hsp70–RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor

Receptor-associating protein 46 (RAP46) is a cochaperone that regulates the transactivation function of several steroid receptors. It is transported into the nucleus by a liganded glucocorticoid receptor where it downregulates DNA binding and transactivation by this receptor. The N- and C-termini of...

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Bibliographic Details
Main Authors: Schneikert, Jean, Hübner, Susanne, Langer, Gernot, Petri, Thomas, Jäättelä, Marja, Reed, Jennifer, Cato, Andrew C.B.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305849/
https://ncbi.nlm.nih.gov/pubmed/11101523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.23.6508
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