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Uptake of all-trans retinoic acid–containing aerosol by inhalation to lungs in a guinea pig model system—A pilot study

Systemic therapies with retinoic acid (RA) can result in toxic side effects without yielding biologically effective levels in target tissues such as lung. The authors adapted a PARI LC Star nebulizer to create a tubular system for short-term inhalation treatment of guinea pigs using a water-miscible...

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Detalhes bibliográficos
Main Authors: Schäffer, Michael W., Roy, Somdutta Sinha, Mukherjee, Shyamali, Ong, David E., Das, Salil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058486/
https://ncbi.nlm.nih.gov/pubmed/21043991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01902141003790155
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