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A Perfect Storm: Converging Paths of Epilepsy and Alzheimer's Dementia Intersect in the Hippocampal Formation
Seizures in the human temporal lobe transiently impair cognition and steadily damage hippocampal circuitry, leading to progressive memory loss. Similarly, the toxic accumulation of Aβ peptides underlying Alzheimer’s Disease triggers synaptic degeneration, circuit remodeling, and abnormal synchroniza...
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058398/ https://ncbi.nlm.nih.gov/pubmed/21214538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02909.x |
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