A Randomized Clinical Trial of MK-0777 for the Treatment of Cognitive Impairments in People with Schizophrenia

BACKGROUND: In a previous pilot study, MK-0777, a GABA(A) α2/α3 partial agonist, was reported to improve delayed memory and cognitive measures of prefrontal cortical function in people with schizophrenia. The current study was designed to further examine the efficacy and safety of MK-0777 for the tr...

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Main Authors: Buchanan, Robert W., Keefe, Richard S. E., Lieberman, Jeffrey A., Barch, Deanna M., Csernansky, John G., Goff, Donald C., Gold, James M., Green, Michael F., Jarskog, L. Fredrik, Javitt, Daniel C., Kimhy, David, Kraus, Michael S., McEvoy, Joseph P., Mesholam-Gately, Raquelle I., Seidman, Larry J., Ball, M. Patricia, McMahon, Robert P., Kern, Robert S., Robinson, James, Marder, Stephen R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058394/
https://ncbi.nlm.nih.gov/pubmed/21145041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.09.052
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